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Research Performance

In 2015 Asia's first clinical study of Embryonic stem cells, retinal cell therapy published.
The world's first the success rate of cloned stem cells dramatically increased.

Notice
Product Indication F&D Pre-Clinical Phase Note
Embryonic Stem Cells Pipelines
Retinal Pigment
Epithelial Cells
(MA09-hRPE)
Stargardt's Macular
Dystrophy (SMD)
Technology transfer & 
Partnership with US
Ocata Therapeutics, Inc.
Age-related Macular
Degeneration (AMD)
Myopic Macular
Degeneration (MMD)
Adult Stem Cells or Somatic Cells Pipelines
Placental Adherent
Stromal Cells (PLX-PAD)
Intermittent
Claudication (IC)
Technology transfer &
Partnership with Israel
Pluristem Therapeutics, Inc.
Umbilical Cord-derived
Mescenchymal
Stem Cells (CB-AC-01)
Acute Cerebral
Infarction
Disk Degeneration
Placenta-derived
Mescenchymal Stem
Cells (CB-AC-02)
Alzheimer's Disease
Global Cerebral Ischemia Investigator Initiated Trial
Traumatic Optic Nerve Investigator Initiated Trial
Adipose-derived
Mescenchymal
Stem Cells 
(CB-AC-03)
Articular Cartilage Injury Investigator Initiated Trial
Disk Degeneration Investigator Initiated Trial
Rheumatoid Arthritis
Diabetes mellitus
Neural Progenitor Cells Parkinson's Disease Investigator Initiated Trial
Immunocytes Recurrent Glioblastoma Investigator Initiated Trial
ovarian cancer Investigator Initiated Trial
liver cancer Investigator Initiated Trial
Dendritic Cells
Patents
Division Contents
Embryonic-derived stem cell Apply embryonic-derived stem cells for various indications by differentiating them to retinal pigment epithelium (RPE) Differentiation to various stem cells including embryonic-derived stem cells, culturing methods, and pharmaceutical composite materials.
Placenta-derived stem cell Separation, culture, and pharmaceutical usage of placenta-derived mesenchymal stem cells for various indications
Umbilical cord-derived stem cell Separation, culture, and pharmaceutical usage of umbilical cord-derived stem cells for various indications
Cord blood Agents including cord blood or cord blood-derived stem cells and its pharmaceutical usage for various indications
Fat-derived stem cell Separation, culture, and pharmaceutical usage of fat-derived stem cells for various indications
Testis-derived stem cell Testis-derived pluripotent stem cell manufacturing methods and its pharmaceutical usage for various indications
Induced pluripotent stem cell
(iPSC)
Induced pluripotent stem cell methods, associated pharmaceutical composite materials, and screening methods
Immunocyte Natural killer cell, dendritic cell, or T lymphocyte manufacturing methods and its pharmaceutical usage for various indications including cancer
Stem cell bank The stem cell bank operation system and its usage
Platform technology Drug screening using stem cells, customized diet suggestion system, and screening system for embryonic stem cell culture
Cosmetics Culture fluid originated from various tissues or cells, such as placenta-derived or stem cell-derived ingredients, and cosmetics composite materials including active ingredients
Cell extract Centrifugation bags, separation devices, etc. for extracting SVF (Stromal Vascular Fraction) or stem cells
Notice
Num. Title Author Journal names Date
1060 A multicenter, randomized, and double-blind phase IV clinical trial to compare the efficacy and safety of fixed-dose combinations of amlodipine orotate/valsartan 5/160 mg versus valsartan/hydrochlorothiazide 160/12.5 mg in patients with essential hyperten LIM SW and 16 others Medicine (Baltimore). Sep-2018
1059 The risk factors of miscarriage and obstetrical outcomes of intrauterine normal pregnancy following heterotopic pregnancy management NAH ED, CHOI DH, KWON HWANG, KIM HC, KANG SH, CHO HY and 2 others Medicine (Baltimore). Sep-2018
1058 Antinatriuretic phenomena seen in children with acute pyelonephritis may be related to the activation of intrarenal RAAS LEE JH, JANG SJ, LEE SK Medicine (Baltimore) Sep-2018
1057 Endovascular management in immature arteriovenous fistula for hemodialysis LEE SJ, LEE JJ, JUN KS and 2 others Medicine (Baltimore) Sep-2018
1056 Sustained drug release using cobalt oxide nanowires for the preparation of polymer-free drug-eluting stents PARK WR, HAN DK and 3 others Journal of Biomaterials Applications Sep-2018
1055 Role of omega-3 polyunsaturated fatty acids in preventing gastrointestinal cancers: current status and future perspectives HAAM KB and 6 others Expert review of anticancer therapy Sep-2018
1054 Meta‐analysis of the Influence of UGT Genetic Polymorphisms on Lamotrigine Concentration KIM MK and 1 other Basic & clinical pharmacology & toxicology Aug-2018
1053 Comparative genomic analysis of the human and nematode Caenorhabditis elegans uncovers potential reproductive genes and disease associations in humans KIM YS, KWAK KB and 2 others Physiological genomics Sep-2018
1052 In Vitro Derivation of Functional Sertoli-Like Cells from Mouse Embryonic Stem Cells PARK SA, LEE DY and 3 others Cell transplantation Sep-2018
1051 Novel TGF‐β1 inhibitor antagonizes TGF‐β1‐induced epithelial‐mesenchymal transition in human A549 lung cancer cells NAH YH and 8 others Journal of cellular biochemistry Sep-2018
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Adipose Stem Cells

Adipose Stem Cells can be easily extracted with liposuction. They are ideal stem cells for the regenerative medicine due to the fact that a large amount of stem cells can be obtained from a relatively small amount of adipose tissues. They have been mainly only used for wrinkle improvement and cosmetic surgeries ; however, they are now widely applied to treat various diseases such as myocardial infarction, diabetes, liver ailment, ischemic peripheral circulatory disorders, urinary incontinence as numerous research outcomes proved that these cells have plenty of mesenchymal stem cells, which are helpful for cell restoration.

Patient - Harvest fat tissues - Adipose tissue(lipoaspirate) - RBC wash or lysis - Well mix with collagenase in shaking incubator - 1st centrifugation for SVF - 2nd centrifugation with N/S then pipette out N/S to wash out ollagenase, 2 times more Harvest thick pellet at bottom - Differentiate Adult Stem Cell - Fat, Bone, Muscle, Cartilage - Injection with fine tube as 1cc in every 1 minute after shaking well the syringe
Definition of SVF Therapy

Adipose tissues are major sources for stem cells.
SVF (Stromal Vascular Fraction) is defined as a therapy to inject stem cells intravenously, and the stem cells (2 to 5x106 units) are safely harvested with the medical instrument from adipose tissues obtained by conducting liposuction on the abdominal region.

Effects of SVF Therapy

The main purpose is the regeneration of stem cells.
In addition, it has a good effect on recovering chronic fatigue and preventing aging as it helps to form abundant growth factors as well as anti-inflammatory factors. Furthermore, there have been many patients who testified that they experienced the improvement of eyesight, erectile function, hair growth.

SVF Programs

Injection to Face To boost forming new blood vessels and collagens with the purpose to improve skin elasticity.
Intra-Venous Injection To improve clinical symptoms relevant to aging with the purpose to have an Anti-Aging effect.
Injection to Joint cartilage In order to reduce inflammation and pain, regenerate the articular cartilage.

Cord blood stem cells are used therapeutically in transplants to help cure, treat and repair damaged blood and immune systems.
Cord blood stem cells are being studied for potential use in regenerative medicine. CHA has been applying the stem cells to Cerebral Palsy patients since 2009 and developing pipeline for Stroke and Alzheimer's. Chaum provides opportunity to participate in the clinical trial for Cord Blood. We expect that this will help stimulate and guide the body's own repair system to heal damaged tissue and organs without any side effects.

Benefits of Cord Blood Clinical Trial

  • Cord Blood has abundant growth factors.
  • Cord Blood has excellent capabilities of differentiation
  • It's clearly proven that there is no adverse effect of transplanting cord blood.
  • CHA Health Systems Group's Cord Blood Bank has total 900 transplanting cases)

Cord Blood Stem Cell Collection & Transplant Process

Cord Blood Bank, ICORD

Cord blood transplant clinical status

It is ongoing to "Randomized, double-blind, placebo-controlled and pre-clinical studies for the potential efficacy and safety about improving clinical aging indicators by injection of Umbilical cord blood or plasma to adults in previous step of decrepitude" approved by the IRB.

Approximately 53% of the participants 84 (including during clinical studies with placebo) until now seemed to improve in the next part.